It had been found that Heinz bodies formation and membrane skeleton disruption in erythrocytes were enhanced after oxidative damage. Oxidized erythrocyte membrane protein band 3 underwent degradation as well as aggregation. 受氧化损伤后,红细胞Heinz小体的产生增加,膜带3蛋白发生降解和聚集,膜骨架被破坏。